Propolis is a brown resinous substance collected by honeybees from tree buds, used by them to fill crevices and to fix and varnish honeycombs. It has a 5000-year history and was even used by the Assyrians, the Egyptians and the Greeks. It offers antiseptic, antibiotic, antibacterial, antifungal, and antiviral properties.
Here is a short video clip describing where propolis comes from and how it is useful:
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Source: http://www.healthline.com/health/propolis-an-ancient-healer